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Contrave is an oral extended-release medication that contains two active ingredients: bupropion (an antidepressant, also found in the medicine Wellbutrin) and naltrexone (an opioid antagonist)

At the cellular level, a big piece of that picture is the steady drop in both NAD+ and glutathione

ALCAR can provide an acetyl moiety that can be oxidized for energy, used as a precursor for acetylcholine, or incorporated into glutamate, glutamine and GABA, or into lipids for myelination and cell growth