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Time to exhaustion was negatively associated with fat mass (r = 0.91) but not with LBM (r = 0.12)

Adding GIP receptor (GIPR) agonism introduces a second incretin pathway that enhances insulin secretion through distinct cAMP signaling, independently modulates adipocyte lipid handling, and engages central appetite circuits through complementary routes to GLP-1R

Ligand engineering approaches, such as site-specific peptide conjugation and fatty acid modifications, enhance receptor affinity and targeting precision

Selena also emphasizes the importance of mental health, practicing self-care through therapy and meditation