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Figure 2b with colour-coded RMSD between crystal structures was generated using the ColorByRMSD Pymol script ( accessed on 16 June 2022)
FSP1 (ferroptosis suppressor protein 1) facilitates the NADPH-dependent reduction of CoQ10 to CoQ10H 2 , a lipophilic radical-trapping antioxidant that prevents lipid peroxidation ( de novo synthesis pathway, works alongside GPX4 to inhibit mitochondrial lipid peroxidation
For those with high levels of oxidative stress or older adults whose internal production has slowed, taking a highly bioavailable glutathione supplement like ours often provides more direct and noticeable support.
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