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Clinical use: Supervised protocols at medical clinics involve subcutaneous injection over 4 to 8 weeks, with dosing individualized to injury type and severity

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The receptor is a glycoprotein that, like all G protein-coupled receptors, has a seven-transmembrane helix domain and an N-terminal extracellular signal peptide [7]

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TH17 cells then produce their own cytokines, primarily IL-17A and IL-22, which act directly on keratinocytes, the cells that make up the outer layer of skin

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