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The FDA also warns not to take Saxenda if you have a personal or family history of multiple endocrine neoplasia syndrome Type 2, medullary thyroid cancer, or insulin-dependent diabetes

Meal timing and eating patterns may affect GLP-1 dynamics, though evidence is still emerging

The compounded semaglutide products provided by Noom are not reviewed by FDA for safety, efficacy, or quality

In an animal model extending 21 days, researchers identified: Lower levels of beneficial gut bacteria that help break down dietary fibre Reduced short-chain fatty acids which protect the gut lining and help regulate inflammation Higher levels of blood inflammatory markers An increase in liver weight, which can reflect low-grade inflammation A smaller caecum the part of the intestine where gut bacteria break down fibre and produce protective compounds Reduced levels of a brain-derived protein associated with cognitive impairment