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Studies show: Elevated IL-6 and TNF- Persistent interferon signatures T-cell exhaustion Altered CD4/CD8 ratios Increased autoantibodies, including anti-nuclear antibodies (ANA) and anti-phospholipid antibodies 5 There is also growing evidence of microglial activation in patients with neurocognitive symptoms, suggesting ongoing neuroinflammation

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Research indicates that growth hormone promotes lipolysis in adipose tissue, particularly in visceral and subcutaneous depots, through activation of hormone-sensitive lipase (HSL) and modulation of lipid droplet protein expression