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A Review of the Effects of Glucagon-Like Peptide-1 Receptor Agonists and Sodium-Glucose Cotransporter 2 Inhibitors on Lean Body Mass in Humans
Factors that should alert clinicians to possible nondiabetic aetiologies include an absence of retinopathy, duration of diabetes less than five years, acute renal injury pattern of renal dysfunction rather than gradual progression, presence of haematuria or other systemic disease and presence of nephrotic syndrome (albuminuria greater than 3 g/day, low serum albumin level, oedema and symptoms such as frothy urine)
Matsui, T
So if someones strongest motivation is to get pregnant, it may be more important to move directly to fertility treatments such as in vitro fertilization (IVF), rather than losing a certain amount of weight first. For women who have not achieved desired weight loss with lifestyle changes, using a GLP-1 medication combined with lifestyle changes can help them move forward with IVF sooner
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