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Medications like Ozempic and other GLP-1s can also affect digestion and the balance of healthy bacteria in your gut (microbiome), which may impact vaginal health and make things like irritation or infections more likely

As a result, the FDA required black box warnings on some GLP-1 medications

In the larger SELECT trial in 2023, patients with heart failure, atherosclerotic disease, and overweight or obesity, treated with semaglutide 2.4 mg showed reduction in major adverse cardiac events (MACE) and heart failure end points regardless of heart failure subgroup being HFrEF or HFpEF [56,57,58]

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