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During this period, the morbidity and mortality patterns change, with chronic diseases becoming more relevant, such as malignant neoplasms, atherosclerosis, osteoporosis, arteriopathies, and neurodegenerative diseases ( The use of HRT dates back to the 1960s
Blood was obtained via cardiac puncture and centrifuged at 4000 rpm at 4 C for 10 min to collect plasma
3.3 Types of ubiquitination and their involvement in circadian regulation The specific architecture and type of ubiquitin linkage play a key role in determining the fate of the modified proteins (Yau and Rape, 2016
doi:10.1186/1745-6215-15-115 Levander OA, Beck MA
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