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IGF-1 quantification Liver tissues were weighed and homogenized in lysis buffer containing PBS, 1% Triton X100 and protease inhibitors (Roche, cOmplete, EDTA-free)

In combination with low-dose GLP-1s, we believe the clinical benefit increases even more, with higher levels of adherence to GLP-1s, and we are confident that by pivoting to this approach, we will capitalize on the success of GLP-1s and set Allurion up for long-term success. The company also announced that it has submitted its protocol for a prospective, multi-centre study on the combination of the Allurion Program with a low-dose of GLP-1 for weight loss while maintaining muscle mass and increasing GLP-1 adherence to Institutional Review Boards (IRBs) in Europe for approval