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Derosa L, Routy B, Thomas AM, et al

[11] A systematic review and meta-analysis found that, using randomized controlled trials, that semaglutide is efficacious for sustained weight loss in patients with overweight/obesity and without diabetes

Ozempic was originally designed to help patients manage their Type 2 diabetes and lower the risk of heart attack, stroke, and heart-related death in those with heart disease and Type 2 diabetes

Category 1 Bulk substance the FDA considers eligible for use in compounding pending final rulemaking Generally permitted Category 2 Bulk substance the FDA has significant safety, identity, or quality concerns about Not permitted during review Category 3 Substance requiring further evaluation Case-by-case Critically, Category 1 status is not FDA approval