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Basic science of appetite

Shanzhiside methylester, the principle effective iridoid glycoside from the analgesic herb Lamiophlomis rotata, reduces neuropathic pain by stimulating spinal microglial -endorphin expression

The observed variations in efficacy across different models underscore the need for comprehensive evaluations using various animal models to fully reveal the efficacy of GLP1-RA drugs and elucidate their mechanisms of action