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3.3.4 Pharmacodynamics After Multiple Doses of Oral Semaglutide In subjects with T2D, a statistically significant decrease in HbA 1c from a mean baseline level of 7.5% was seen after 10 weeks of treatment with 40 mg oral semaglutide versus placebo (treatment difference in change from baseline 1.5% [95% CI 1.8, 1.3]

Semaglutide GLP-1 is part of a class of drugs known as glucagon-like-peptide 1 receptor antagonists, or simply GLP-1 receptor antagonists

It is important to distinguish between direct pharmacological effects on erectile tissue and secondary improvements resulting from better metabolic health