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This tolerance-building process is analogous to allergy immunotherapy, where repeated exposure to an allergen gradually desensitizes the immune system

A mutant for the lysosomal copper transporter gene slcr-46.1 exhibited defective cold tolerance due to copper accumulation in the pharyngeal muscle upon cold exposure

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Rhodiola rosea is known to elevate monoamine concentrations and modulate pathways involved in the stress response, whereas Ginkgo biloba is recognized for its ability to enhance cerebral perfusion, safeguard against oxidative damage, and facilitate synaptic plasticity