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The treatment with ALCAR [67, 68, 69]: Reduced depression and improved cognitive function Enhanced social function and general wellbeing Lowered the levels of ammonia and improved other biomarkers 7) Fatigue In 96 older people, supplementation with acetyl-L-carnitine (ALCAR) improved [54]: It also boosted mood and mental clarity while causing no side effects

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In contrast to prior studies 9,12,14,15 , which primarily relied on baseline or intention-to-treatstyle exposure definitions, AHM exposure in the present study was measured throughout the follow-up, and participants with high exposure ( 80% PDC) of the medication class were grouped under the class and compared, an approach not utilised in previous studies 9,12,13,15,31

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