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Read the full article on the MRGPRX2 receptor here

The copper-bound tripeptide (glycyl-L-histidyl-L-lysine) has an extraordinarily high copper binding affinity with a pK of 16.44, which is approximately 10 million times higher than other tripeptides

If you have additional risk factors, such as a vegetarian or vegan diet (which may be lower in B12-containing foods), a history of gastrointestinal surgery, or certain medical conditions like pernicious anemia, your healthcare provider may recommend monitoring your B12 levels and considering supplementation, including B12 shots if necessary