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Regulatory pathway: no IND application filed, no clinical trials registered

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The oral capsule format is designed for gastrointestinal pharmacology studies investigating local GI effects (gastric ulcer models, IBD models) and systemic bioavailability via the oral route

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Upon proteolytic degradation, these residues undergo a series of enzymatic reactionsincluding hydroxylation, aldol cleavage, and aldehyde oxidationleading to the formation of 4-trimethylaminobutyric acid (-butyrobetaine), which is subsequently converted into l-carnitine through the catalytic action of -butyrobetaine dioxygenase (BBOX1) 25,26

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