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Dietary and Lifestyle Strategies to Prevent Constipation Increasing water intake is the most underutilized and effective constipation prevention method for people on semaglutide

Although gut function is clearly integral to human and animal health, there are many unresolved issues relating to gut health

(C) Representative dot blots of NO 2 -tyr signals

Common adverse effects , particularly during dose escalation, include: Nausea (reported by 2050% of patients, usually mild to moderate) Vomiting, diarrhoea, or constipation Abdominal discomfort or bloating Reduced appetite (therapeutic effect, but may feel unusual initially) Fatigue or headache These effects typically diminish over several weeks as tolerance develops