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In March 2025, Roche and Zealand Pharma launched an Up-to-$5.3B obesity collaboration to co-develop and co-commercialize Zealands petrelintide for overweight and obesity indications

The AME will review the FAAs Weight Loss Management Worksheet Special Issuance Conditions (diabetes): Tirzepatide (Mounjaro) , even as a single agent, requires Special Issuance due to its unique dual-action mechanism

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This substantial inventory build signals management's confidence in regulatory approval and represents a decisive effort to avoid repeating the supply constraints that plagued earlier product rollouts [4]