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CLINICAL IMPLICATIONS AND FUTURE DIRECTIONS For clinicians managing patients with MASH and F2-F3 fibrosis, ESSENCE positions semaglutide 2.4 mg weekly as an attractive option for patients with obesity and/or T2DM and high cardiometabolic risk [7]

A growing body of evidence confirms that GLP-1 can indeed help people lose weight, even if they have type 2 diabetes

We also recognize that the evidence is less conclusive for individuals with normal B12 levels

When we evaluate a potential pass-through device to determine whether it meets the device category criterion at 419.66(c)(1), we compare the nominated device to the device category descriptor rather than to the specific device for which the device category was created