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Guidance on hydration (6480 oz/day), protein, fiber, and movement

As Ube2d3 was detected in the mass spectrometry, we also examined its potential association with DET1 and COP1

First-line treatment typically involves: Methotrexate the most commonly prescribed conventional synthetic DMARD Sulfasalazine or hydroxychloroquine alternative or combination options Leflunomide for patients who cannot tolerate methotrexate These medications are usually combined with short-term corticosteroids (such as prednisolone) to provide rapid symptom relief whilst DMARDs take effect, which can take several weeks to months