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Some people experience constipation because the colon absorbs more water from slower-moving contents

Notably, although tetramers are generated at high protein concentrations, the truncation of either of the two key hydrophobic residues (Leu-344 and Leu-348) can shift the oligomerization state toward the formation of a stable dimer

Contact your prescribing clinician, dispensing pharmacist, or clinical trial coordinator for advice before proceeding

For oral administration, polymeric nanoparticles offer controlled release and high drug-loading potential, but are prone to protein corona formation in vivo , which compromises targeting capabilities