GLP-1 is a glucose-dependent intestinal hypoglycemic peptide hormone secreted by L cells in the terminal jejunum, ileum and colon
Joshi GP, Abdelmalak BB, Weigel WA, Harbell MW, Kuo CI, Soriano SG, et al
There is a large body of preclinical studies that provide compelling evidence of a functional BTR signaling system in enteroendocrine cells, the effects of non-nutritive BTR agonists on enteroendocrine hormone secretion, and the potential for stimulating intestinal BTRs to suppress energy intake and reduce postprandial glycemic excursions ( Relative to STRs (T1R2/T1R3) and umami taste receptors (T1R1/T1R3), the biology of BTRs (T2Rs) appears to be more complex due to their diversity
When food moves through your stomach more slowly than your body is used to, the result is nausea, bloating, and digestive discomfort