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2.4 Association between increased glycolysis with clinical response and survival rates in ALs Despite the strong evidence that glycolytic metabolism can promote chemoresistance in primary leukemic cells from non-responders and/or multiresistant cell lines, recent advances in metabolomics platforms have allowed further investigation into tumor metabolism at the systemic level in patients with acute leukemia (Grnningster et al., 2019

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By promoting actin polymerisation, TB-500 facilitates cell migration to sites of injury a foundational step in tissue repair cascades