Behavioral assessments (open-field, self-grooming, social interactions) were followed by biochemical and molecular analyses in the cerebellum, where oxidative stress markers (MDA, GSH, SOD, CAT, and GPx) were quantified spectrophotometrically, and Nrf2, Bax, Bcl-2, and Caspase-3 mRNA levels were measured by q RT-PCR
While originally studied for its effect on the pineal gland, researchers have experimented with its overall well-being
Low GSH is not just a consequence of insulin resistance it may also feed the cycle, worsening mitochondrial dysfunction and impairing insulin signaling
Metabolic imbalances Thyroid hormones are key regulators of metabolic balance, and elevated thyroid hormones can significantly impact energy-making processes, cardiovascular function, temperature regulation, and body composition