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Exp Gerontol

Commonly reported side effects in the Phase 2 trial included: Nausea (the most frequently reported adverse effect) Vomiting Diarrhoea Constipation Decreased appetite Abdominal discomfort or bloating Eructation (belching) The majority of participants who discontinued treatment did so due to gastrointestinal side effects, underscoring the importance of the slow titration schedule used in trials

PCOS affects your metabolic health in ways that go far beyond what BMI can measure

Recent studies have highlighted their potential roles in improving insulin sensitivity, modulating gastric emptying, and influencing satiety signaling through the gut-brain axis