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They dont have to have tests or clinical trials or whatever to show they work, but they cant be harmful, and they cant make disease claims. CNNs John Bonifield contributed to this report.

[PubMed: 27151488] (49 year old woman developed jaundice 4 weeks after starting Hydroxycut for weight loss [bilirubin 6.9 mg/dL, ALT 115 U/L, Alk P 299 U/L], which improved after stopping but was followed by persistent Alk P elevations [237 to 253 U/L] without jaundice while liver biopsy showed bile duct loss)

However, modern advancements in bio-fermentation have fundamentally challenged this dogma

As weight loss and diabetes drugs like Ozempic, Wegovy and Mounjaro increase in popularity, more users are learning about the risk of potentially serious gastrointestinal side effects associated with the medications, and are choosing to cut back on their dosages without consulting their doctors