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Practical roadmap and regional gaps At present, no formal clinical algorithm exists in Saudi Arabia or other regional settings to guide GLP-1 RA management in women planning pregnancy

5.2 Animal models In animal models of Cushings syndrome and associated obesity, the simplest model is the excessive administration of exogenous GCs to rodents by s.c., i.p., i.m

It is also active in the brain, where the receptors it binds to cluster in regions governing reward, motivation and stress the same circuitry that gets hijacked by addiction