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This step is where TK and TK modelling become essential providing tools for bridging internal and external exposure metrics

They, therefore, suggested administering a second dose of PRP where necessary at about three months in the case of partial recovery as a boost dose [23]

Ishikawa, K

doi: 10.3389/fendo.2025.1762825 Received 08 December 2025 Revised 30 December 2025 Accepted 31 December 2025 Published 06 February 2026 Volume 16 - 2025 Edited by Antoni Sureda, University of the Balearic Islands, Spain Reviewed by Elisa Dietrich, Sapienza University of Rome, Italy Lara Russo, National Research Council (CNR), Italy Updates Copyright 2026 Yu, Ge, Fu and Zhao