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(2019) Cystathione beta synthase deficiency and brain edema associated with methionine excess under betaine supplementation: Four new cases and a review of the evidence, JIMD reports, Vol

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In Drosophila , both overexpression and knockdown of Ube3a in central clock neurons resulted in pronounced alterations in circadian locomotor rhythms, indicating that tight regulation of Ube3a levels is essential for proper pacemaker function across species (Gossan et al., 2014