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SKU: 23366333970
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SKU: 23366333970

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Of the eight GPxs, GPx4 is essential for life as the mice lacking it (knock out or KO) do not survive [1, 8, 9]

[DOI] [PubMed] [Google Scholar] 212.Naylor R.J., Olley J.E

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These Cu I binding properties are potentially consistent with a role in Cu storage under Cu-replete or Cu-toxic conditions, 898 or as part of an anticipatory Cu-toxicity response, when cells are chronically metal-starved, and thus particularly vulnerable to mismetalation mediated by even modest Cu toxicity (see Section 5.3.2)