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Trichothecenes: Roridin E (ROE), Verrucarin A (VRA) Tricothecenes are extremely potent inhibitors of protein synthesis and have been described to have wide-ranging negative systemic effects including immunotoxicity (immunosuppression), gastrointestinal toxicity, neurotoxicity, and dermatologic manifestations

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Ideal candidates typically include: Body composition goals: Individuals focused on reducing body fat percentage while preserving lean muscle mass, those who have reached plateaus with diet and exercise alone, patients seeking metabolically selective approaches without growth hormones broader effects, or individuals interested in targeted fat reduction (particularly abdominal/visceral fat)