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Hazen explains that early studies showed that niacin alone could help lower LDL cholesterol, and even lower cardiac risks in subjects with very high levels of cholesterol

The odds ratio was slightly above , but it was not conclusive. Based on these findings, the researchers concluded that GLP-1 receptor agonists could be used as a safe adjunctive therapy for smoking therapy by mitigating the weight gain that typically comes with quitting, particularly for patients who are more prone to relapse or otherwise vulnerable