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Serious but rare gastrointestinal complications that require medical attention include: Pancreatitis (rare but requires immediate medical attention) Gallbladder disease including cholecystitis (risk may be increased with rapid weight loss) Severe delayed gastric emptying Intestinal obstruction or ileus (FDA labels for semaglutide include postmarketing reports of ileus) These conditions require prompt evaluation but are not cancer-related

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In March, the FDA issued a warning letter to Novo Nordisk, the maker of Ozempic and Wegovy, alleging the company failed to properly report certain adverse events, including reports involving suicidal ideation and deaths

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