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Serious but rare adverse effects may include: Pancreatitis Gallbladder disease Kidney injury Thyroid C-cell tumors (observed in rodent studies) Semaglutide is contraindicated in individuals with a personal or family history of medullary thyroid carcinoma or multiple endocrine neoplasia syndrome type 2

Consequently, we can expect theoretically higher levels of nausea and vomiting that is more primarily a function of short term Cmax with this class of molecule

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