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glabra L (Gancao), can inhibit the CCL2/CXCR4 axis to reduce M2 macrophage infiltration, while downregulating HMOX1/NOX4 to inhibit ferroptosis, and regulating the PPAR signaling pathway and fatty acid metabolism, thus forming immune-metabolic synergistic regulation (Shi et al., 2024)

Racette et al., 2001

While it has been well documented that glutathione plays a central role in the antioxidant network in animal cells and redox balance can act as a marker of antioxidant status in various pathological and physiological conditions including exercise [3,4,14,15], the role of exogenous glutathione on phenotypic changes relating to physical exercise has not been explored