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The neuroprotective effect of GLP-1R agonists is that it can either directly/locally cause neuroprotection by acting on neuronal tissue or indirectly/systemically cause neuroprotection by improving glycemic control and treating existing insulin resistance (Figure 3) ( FIGURE 3 Alzheimers Disease Several early studies have identified the presence of cognitive impairment in patients with T2D (Perlmuter et al., 1984

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Donna Ryan del Centro de Investigacin Biomdica Pennington en Baton Rouge, Luisiana, observaron que la tendencia mostraba que los participantes que tomaban el medicamento generalmente perdan peso durante aproximadamente 65 semanas, o un ao y tres meses, antes de alcanzar una meseta