semaglutide anaphylaxis These highlights do not include all the information needed to use RYBELSUS ® and OZEMPIC® tablets safely and effectively. See full prescribing information for RYBELSUS and OZEMPIC tablets. RYBELSUS (semaglutide) tablets, for Frontiers | Safety of Semaglutide

In several clinical trials involving Semaglutide, some participants reported experiencing GI issues

Congestive heart failure Severe thiamin deficiency (wet beriberi) can lead to impaired cardiac function and ultimately congestive heart failure (CHF)

Future directions and research gaps Although GLP-1 therapies have revolutionized obesity and diabetes management, important knowledge gaps remain in optimizing their long-term safety, tolerability, and body composition outcomes

Research has suggested that low iron levels may be the underlying factor in decreased carnitine levels during pregnancy (as iron is a needed cofactor in the synthesis of carnitine in the body)