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Unlike other drug trials, integrative oncology studies encounter additional methodological issues such as the plethora of supplement formulations and their composition, variability in concentration of bioactive compounds across different source materials, patient-driven simultaneous use of products and multifaceted endpoints that include tumour response objective assessments as well as symptom control, quality-of-life evaluation, and biomarker modification (19)

Mitochondrial regulation in stem cells

Testing every 6 months for those with severe thalassemia or B12 deficiency symptoms