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Although molecular mechanisms are not explicitly described, the authors highlight that these biomarkers are reliable indicators of the anti-inflammatory and antioxidant potential of GLP-1RAs, which may contribute to their cardioprotective and renoprotective actions in inflammatory conditions such as sepsis (35)

Insulin resistance due to metabolic syndromes can influence body systems and cause inflammation and hypertension [11]

The current evidence base for GLP-1 receptor agonist therapy is derived from extensive clinical trial programmes that have established the efficacy and safety of specific, licensed doses