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The as-1 promoter element is an oxidative stress-responsive element and salicylic acid activates it via oxidative species

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That delay is dangerous because the differential diagnosis includes conditions that can require urgent treatment, including: Giant cell arteritis (vision- and life-threatening) Retinal detachment Central retinal artery occlusion Optic neuritis Acute angle-closure glaucoma Stroke-related visual pathway events The correct pathway is not wait and see. The correct pathway is urgent evaluation by emergency services or immediate ophthalmology or neuro-ophthalmology assessment