M., Gianfrilli, D., Moretti, C., Caprio, M., & Watanabe, M
Secondary Outcomes: Metabolic Improvements: Waist circumference: Average reduction of 13.3 cm (5.2 inches) Blood pressure: Systolic reduced by 6.6 mmHg, diastolic by 2.8 mmHg Triglycerides: Reduced by 28% HDL cholesterol: Increased by 11% HbA1c (blood sugar marker): Reduced by 0.4% in non-diabetics C-reactive protein (inflammation): Reduced by 42% Quality of Life: Significant improvements in SF-36 physical functioning score Better scores on Impact of Weight on Quality of Life questionnaire Improved mobility and reduced pain Enhanced psychological well-being SURMOUNT-2 Trial: Tirzepatide in Type 2 Diabetes Study Overview: Participants: 938 adults with obesity and type 2 diabetes Duration: 72 weeks Design: Randomized, double-blind, placebo-controlled Primary Results: Weight Loss by Dose: Key Finding: Diabetic patients lost slightly less weight than non-diabetics but still achieved substantial weight loss plus improved blood sugar control
Combined with diet and exercise, semaglutide can be an effective tool in controlling diabetes and improving overall health
On top of that, we know that only a small percentage of vitamin B12 taken orally is actually absorbed
