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Since the -2 subcluster is composed of cells exhibiting transcriptional signs of stress and the proportion of this subcluster was decreased upon liraglutide treatment, these data suggest that liraglutide-induced expression of XBP1 in the -1, -3, and -4 subclusters is a reflection of its protective action

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Cognitive improvements were evident at doses of 200, 400, and 800 mg/kg/day, as confirmed by passive avoidance and Y-maze tests (Lim et al., 2018)