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Similarly, in the A Heart Disease Study of Semaglutide in Patients With Type 2 Diabetes (SOUL) study, which randomized patients with type 2 diabetes and atherosclerotic cardiovascular disease, chronic kidney disease, or both to oral semaglutide versus placebo, the primary outcome of major adverse cardiovascular event occurred in 12.0% of the patients receiving semaglutide and 13.8% of the patients receiving placebo (hazard ratio, 0.86

Supportive Strategies for Managing Dry Mouth while taking GLP-1s Stay Hydrated : Regularly sipping water throughout the day can help alleviate dry mouth symptoms

Nausea, vomiting, and digestive discomfort were still the most common side effects

Nested basket cohorts within the same registrational program measured knee osteoarthritis pain on the WOMAC scale and obstructive sleep apnea severity on the apnea-hypopnea index, with Lilly reporting up to 73.1 percent pain-score improvements and up to 60.6 percent AHI reductions at 80 weeks in topline ADA releases