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GHK-Cu is the copper(II) complex of the human tripeptide glycyl-L-histidyl-L-lysine (Gly-His-Lys)

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The peptide exhibits a favorable pharmacokinetic profile with predictable absorption and distribution

The fact that of all tested tissues, we identified T H 17 cells accumulating solely in Pps and dural meninges of 5xFAD mice, suggests that gut-educated CD4 + T cells may be a source of disease-associated IL-17A during AD, supporting a gut-brain axis in which T H 17 cells, induced in intestine-associated tissues, could drive neuroinflammation 76 and promote worsening of cognition 77