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Below is a summary of typical profiles and when they tend to occur during treatment initiation and titration

Moreover, recent studies suggest that the induction of cellular senescence, rather than the promotion of apoptosis through radiotherapy or chemotherapy, might be the main mechanism for impairing the self-renewal capacity of cancer cells, particularly in the context of solid tumors [55]

As previously described, genetic testing strategies were related to high efforts and costs and often disappointing regarding safety or outcome (151153)

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