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The Benefits of Early GLP-1 Use: Frequently Asked Questions How do you know if you would benefit from a GLP-1 medication
Nat Med (2018) 24(2):194202
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In a mouse model of colitis, royal jelly acid significantly reduced the expression of key inflammasome components, including TXNIP, NLRP3, ASC, Caspase-1, GSDMD, N-GSDMD, IL-1, and IL-18, while in THP1 cells, it inhibited LPS/ATP-induced inflammasome-mediated pyroptosis, thereby alleviating inflammation and associated colitis ( in vitro and in vivo , more studies are necessary to explore its potential mechanisms in different inflammatory and related conditions
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