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doi:10.1038/ng.3696 Lyons JJ, Greiner G, Engel N, et al

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The unexpected paradoxical worsening of psoriatic lesions after treatment with liraglutide was hypothesized to be due to cytokine imbalance with the release of IFN- and leukocyte chemotaxis after liraglutide-induced inhibition of TNF-, IL17, and IL23