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These data are particularly interesting since earlier stimulation studies support the role of DBS in promoting neurogenesis through findings that electrical fields can (1) selectively direct the migration of stem cells [377,378,379], (2) increase blood flow [380], and (3) modulate neural networks (see sections by Cooperrider, Manto and Oulad Ben Taib, Bradnam and McCambridge, Popa and Hallett, and Timmann and Nitsche)

Many methodological validations were not included because of the limited space of the article