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It serves as a coenzyme in over 100 enzymatic reactions, most of them involving amino acid metabolism, neurotransmitter synthesis, and glycogen breakdown

This simple alignment does not eliminate fatigue, but it ensures that fatigue occurs when it is least consequential

While previous studies highlighted some of these risks in patients with diabetes, this is the first large, population-level study to examine adverse gastrointestinal events in non-diabetic patients using the drugs specifically for weight loss

Several studies posit an anti-inflammatory and anti-apoptotic role of GLP-1 in both preventing and reducing the progression of DR